Huntington's chorea is a devastating neurological disease in which a faulty gene produces messenger RNA which codes for a toxic protein that gradually destroys the brain. A recent, smallish trial has, however, generated some very encouraging results. Here, a synthetic strand of DNA is injected into the brain that 'kills' the messenger RNA and reduces the production of the toxic protein, slowing the progression of the disease (https://www.theguardian.com/science/2017/dec/11/excitement-as-huntingtons-drug-shown-to-slow-progress-of-devastating-disease). This is not a cure but the slowing of symptoms may not only be good news for Huntington's sufferers as the technology (using variants of synthetic DNA) may also be applicable to patients with Alzheimer's dementia and Parkinson's disease (there also appear to be faulty proteins in these conditions).
This blog may help people explore some of the 'hidden' issues involved in certain media treatments of environmental and scientific issues. Using personal digital images, it's also intended to emphasise seasonal (and other) changes in natural history of the Swansea (South Wales) area. The material should help participants in field-based modules and people generally interested in the natural world. The views are wholly those of the author.
Monday, 11 December 2017
Shoot the Messenger?
Huntington's chorea is a devastating neurological disease in which a faulty gene produces messenger RNA which codes for a toxic protein that gradually destroys the brain. A recent, smallish trial has, however, generated some very encouraging results. Here, a synthetic strand of DNA is injected into the brain that 'kills' the messenger RNA and reduces the production of the toxic protein, slowing the progression of the disease (https://www.theguardian.com/science/2017/dec/11/excitement-as-huntingtons-drug-shown-to-slow-progress-of-devastating-disease). This is not a cure but the slowing of symptoms may not only be good news for Huntington's sufferers as the technology (using variants of synthetic DNA) may also be applicable to patients with Alzheimer's dementia and Parkinson's disease (there also appear to be faulty proteins in these conditions).
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