Tuesday, 20 May 2025

Weight Loss Revolution?

 


Semaglutid and tizepatide are active ingredients in the so-called 'weight loss' drugs. They basically mimick  glucagon-like peptide -1 (GLP-1). GLP-1 is a natural hormone helping to control of blood glucose levels (and, hence diabetes mellitus). It also markedly suppresses appetite. Reduced food intake naturally generates a weight loss (https://www.theguardian.com/news/ng-interactive/2025/may/17/weight-loss-drugs-altering-views-how-body-brain-work). Helping folk to attain a healthy weight is obviously beneficial. It reduces the incidence of diabetes, strokes and cardio-vascular disease. 'Weight loss' drugs are also big money-spinners for their manufacturers. Having said that, one can't stress too strongly the view that medicalising all weight loss has its downsides. Folk may well get a sub-optimal diet. There's really no substitute for a healthy life-style, with a balanced intake of foods and appropriate levels of exercise.

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