Thursday 11 March 2021

Covid Children?

Unlike the preparations for Polio and the MMR, the Covid-19 vaccines have not been assessed for use in children. This, seems mainly a consequence of the early observation in the Covid-19 pandemic, that children were much less likely to become seriously ill (and die) than older patients. There was a need for speed, when developing these Covid-19 vaccines. Using mature subjects, in the controlled studies required for approval of the preparations, was faster, as subjects could give informed consent. It would, however, be very useful to be able to give Covid-19 vaccinations to children. Firstly, to achieve 'herd immunity' for populations and secondly, because everyone wants to resume education (at all levels), as soon as possible. There is some encouraging news coming out of Israel on children and the vaccine (https://www.theguardian.com/society/2021/mar/10/israel-says-600-children-given-covid-jab-had-no-serious-side-effects). Israel has managed to vaccinate a very substantial proportion of its population. In their roll-out, they gave the Pfizer/BioNTech vaccine to about 600 children. These children had underlying health conditions, like cystic fibrosis. They were, consequently, feared to be especially vulnerable, if they contracted Covid-19. No major side-effects were seen in this group of children. Even mild reactions, were rare. These observations (it's not a controlled experiment) suggest the vaccine is safe in this age group. Both Pfizer and AstraZeneca are planning controlled studies with their vaccines in children. It will, however, be several months before any data is obtained. The abilities of vaccines to a) protect and b) reduce transmission by children, need serious investigation. The earlier vaccination can be safely done, the better.

No comments:

What's In a Critter's Name? 17. Goose barnacle

Nobody had ever seen a migratory Barnacle goose nest or lay eggs. Folk, consequently, decided they must emerge, by spontaneous generation, ...