This blog may help people explore some of the 'hidden' issues involved in certain media treatments of environmental and scientific issues. Using personal digital images, it's also intended to emphasise seasonal (and other) changes in natural history of the Swansea (South Wales) area. The material should help participants in field-based modules and people generally interested in the natural world. The views are wholly those of the author.
Wednesday 27 January 2021
Monoclonal Cocktails and Covid-19
There is some encouraging news on the use of cocktails of monoclonal antibodies, in so-called 'passive immunisation'. In this treatment, patients get ready-made antibodies, rather than being stimulated to produce their own by vaccination (https://www.reuters.com/article/us-health-coronavirus-regeneron-pharms-idUSKBN29V1DY?utm_campaign=trueAnthem%3A%20Trending%20Content&utm_medium=trueAnthem&utm_). Regeneron Pharmaceuticals have reported a trial of their 2-antibody cocktail REGEN-COV. The preparation was given to 400 participants, living in households, where a member was already infected with Covid-19. It produced 100% reduction in symptomatic infection and a roughly 50% decline in overall infection. Eli Lilley have claimed that, in a trial, their bamlanivimab preparation cut the risk of a Covid-19 infection by 80% in vulnerable nursing home residents. There was a death and a hospitalisation in the placebo group but people getting active preparations were fine. It's still early days but things are looking good for these preparations. They are likely to become a treatment of last resort.
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