This blog may help people explore some of the 'hidden' issues involved in certain media treatments of environmental and scientific issues. Using personal digital images, it's also intended to emphasise seasonal (and other) changes in natural history of the Swansea (South Wales) area. The material should help participants in field-based modules and people generally interested in the natural world. The views are wholly those of the author.
Saturday, 18 February 2023
Getting to Grips With Our 'Rogue' Bits of DNA?
Extra chromosomal DNA (ecDNA) are small sections of these nucleotides, acting outside the normal genetic rules. Recent evidence, suggests ecDNA fragments help cancers to spread. These small sequences may even allow tumours to become resistant to anti-cancer drug treatments (https://www.theguardian.com/science/2023/feb/18/bond-villain-dna-could-transform-cancer-treatment-scientists-say). As ecDNAs sometimes act as cancer-causing genes, understanding them is likely to have great relevance to our accumulating knowledge concerning how tumours develop and spread within the body. It seems that we are finally closing in on effective treatments for human cancers.
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