Tuesday, 29 March 2022

Personalised Prescriptions?

In the UK, by the age of 70, 90% of people are routinely taking at least one medication. These compounds include common painkillers; drugs to limit the risk of coronary heart disease/stroke and antidepressants. Circa 7% of UK hospital admissions, are actually triggered by adverse drug reactions. Many prescription medicines are also only efficacious in between 30 and 50% of the people who receive them. 99% of people carry at least one genetic variation that alters their response to particular drugs. The British Pharmacological Society and the Royal College of Physicians are arguing the case for pharmacogenomic testing (https://www.theguardian.com/science/2022/mar/29/experts-push-for-genetic-testing-to-personalise-drug-prescriptions ). Pharmacogenomic testing would enable medics to make personalised prescriptions based on the patient's genes. If instituted, such testing would reduce medical side-effects. Pharmacogenomic testing would also reduce the wasteful prescribing of ineffective medications. Such testing would, however, be quite difficult to set up (it would be a major undertaking). There might also be confidentiality issues linked to the collected data?

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